Amphotericin B Amphotericin B : Isolate Amphotericin B of Aktinomaysan can be used systemically, but it has a small therapeutic index.
- A deadly fungal Fungicidal Against the types of fungi and internal mechanism of action ß Has high affinity for union with receptors Ergosterol Located on the cell membrane of the fungi and this leads to change permeability of fungal bacteria which leads to escape potassium and cellular components.
- Uses: Mushrooms Burama Blastomycosis And Hustoblasmozz Histoplasmosis And fungal Sphericity Coccidiomycosis Candida and meningococcal disease malignant And given intravenous slow IV Aimits oral and have a detrimental effect on the kidneys.
